Irina Esterlis Selected Research

SAM-760

2/2023

Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT6 receptor occupancy from non-human primates to humans.

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Irina Esterlis Research Topics

Disease

7	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2023 - 01/2017
6	Major Depressive Disorder (Major Depressive Disorders) 01/2024 - 08/2012
5	Mental Disorders (Mental Disorder) 01/2023 - 11/2020
4	Wounds and Injuries (Trauma) 01/2023 - 01/2017
4	Schizophrenia (Dementia Praecox) 01/2018 - 03/2012
3	Bipolar Disorder (Manic Depressive Psychosis) 01/2023 - 11/2013
3	Pain (Aches) 03/2013 - 12/2009
2	Mood Disorders (Mood Disorder) 01/2023 - 07/2016
2	Alcoholism (Alcohol Abuse) 01/2022 - 06/2011
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2024
1	Alzheimer Disease (Alzheimer's Disease) 02/2023
1	Substance-Related Disorders (Drug Abuse) 01/2023
1	Obesity 01/2022
1	Cognitive Dysfunction 01/2021
1	Necrosis 01/2021
1	Inflammation (Inflammations) 10/2020
1	Tobacco Use Disorder (Nicotine Dependence) 01/2018
1	Treatment-Resistant Depressive Disorder 01/2016
1	Neuroinflammatory Diseases 10/2013
1	Body Weight (Weight, Body) 04/2013
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 04/2011

Drug/Important Bio-Agent (IBA)

9	Metabotropic Glutamate 5 ReceptorIBA 01/2024 - 01/2017
8	Nicotine FDA Link 01/2023 - 04/2011
6	Glutamic Acid (Glutamate)FDA Link 01/2023 - 01/2017
6	Ketamine FDA LinkGeneric 01/2022 - 01/2016
5	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 09/2014 - 05/2010
4	Antidepressive Agents (Antidepressants)IBA 01/2022 - 01/2016
4	Proteins (Proteins, Gene)FDA Link 12/2020 - 10/2013
3	Biomarkers (Surrogate Marker)IBA 02/2024 - 12/2020
3	gamma-Aminobutyric Acid (GABA)IBA 03/2013 - 12/2009
2	Cholinergic Agents (Cholinergics)IBA 07/2016 - 11/2013
2	GABA-A Receptors (GABA(A) Receptor)IBA 03/2013 - 12/2009
1	SAM-760IBA 02/2023
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	Tumor Biomarkers (Tumor Markers)IBA 01/2021
1	InterleukinsIBA 01/2021
1	Blood Glucose (Blood Sugar)IBA 01/2021
1	LipidsIBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	C-Reactive ProteinIBA 12/2020
1	Glucose (Dextrose)FDA LinkGeneric 10/2020
1	SmokeIBA 01/2018
1	GlucocorticoidsIBA 01/2017
1	ProteomeIBA 07/2016
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2016
1	N-Methylaspartate (NMDA)IBA 01/2016
1	Antipsychotic Agents (Antipsychotics)IBA 09/2014
1	Acetylcholine (Acetylcholine Chloride)FDA Link 11/2013

Therapy/Procedure

1	Self Medication 01/2018
1	Intravenous Administration 04/2013
1	Nebulizers and Vaporizers (Inhaler) 04/2011